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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VWF All Species: 11.82
Human Site: S2232 Identified Species: 52
UniProt: P04275 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04275 NP_000543.2 2813 309263 S2232 S S C G D H P S E G C F C P P
Chimpanzee Pan troglodytes XP_001160508 2813 309213 S2232 S S C G D H P S E G C F C P P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540775 3626 389201 A2775 I Y Q Q T D L A G H C Y Y A M
Cat Felis silvestris
Mouse Mus musculus Q8CIZ8 2813 309250 S2232 S F C G D H P S E G C F C P Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q2PC93 5255 560538 E4167 C R E E E H C E P G C R C P N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665356 2857 313308 T2279 S V C L N T P T E G C F C P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 N.A. 24.8 N.A. 83.1 N.A. N.A. N.A. 20 N.A. 44.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 N.A. 37.8 N.A. 90.8 N.A. N.A. N.A. 29.9 N.A. 61.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 6.6 N.A. 86.6 N.A. N.A. N.A. 33.3 N.A. 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 20 N.A. 86.6 N.A. N.A. N.A. 40 N.A. 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 17 0 0 0 0 0 17 0 % A
% Cys: 17 0 67 0 0 0 17 0 0 0 100 0 84 0 0 % C
% Asp: 0 0 0 0 50 17 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 17 17 17 0 0 17 67 0 0 0 0 0 17 % E
% Phe: 0 17 0 0 0 0 0 0 0 0 0 67 0 0 0 % F
% Gly: 0 0 0 50 0 0 0 0 17 84 0 0 0 0 0 % G
% His: 0 0 0 0 0 67 0 0 0 17 0 0 0 0 0 % H
% Ile: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 17 0 0 17 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % M
% Asn: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 17 % N
% Pro: 0 0 0 0 0 0 67 0 17 0 0 0 0 84 34 % P
% Gln: 0 0 17 17 0 0 0 0 0 0 0 0 0 0 17 % Q
% Arg: 0 17 0 0 0 0 0 0 0 0 0 17 0 0 0 % R
% Ser: 67 34 0 0 0 0 0 50 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 17 17 0 17 0 0 0 0 0 0 0 % T
% Val: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 17 0 0 0 0 0 0 0 0 0 17 17 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _